Categoria
Oxaloplatino [Spanish]
Nombres de marca,
Oxaloplatino [Spanish]
Analogos
Oxaloplatino [Spanish]
Marca los nombres de mezcla
No information avaliable
Oxaloplatino [Spanish]
Formula quimica
C8H12N2O4Pt
Oxaloplatino [Spanish]
RX enlace
http://www.rxlist.com/cgi/generic/eloxatin.htm
Oxaloplatino [Spanish]
FDA hoja
Oxaloplatino [Spanish]
MSDS (hoja de seguridad de materiales)
Oxaloplatino [Spanish]
Sintesis de referencia
No hay información disponible
Oxaloplatino [Spanish]
Peso molecular
395.27 g/mol
Oxaloplatino [Spanish]
Punto de fusion
No information avaliable
Oxaloplatino [Spanish]
H2O Solubilidad
No hay información disponible
Oxaloplatino [Spanish]
Estado
Solid
Oxaloplatino [Spanish]
LogP
No information avaliable
Oxaloplatino [Spanish]
Formas de dosificacion
No hay información disponible
Oxaloplatino [Spanish]
Indicacion
Para el tratamiento de neoplasias malignas de colon, recto y ovario
Oxaloplatino [Spanish]
Farmacologia
Oxaliplatino inhibe selectivamente la síntesis del ácido desoxirribonucleico (ADN). El contenido de guanina y citosina se correlaciona con el grado de oxaliplatino inducida por entrecruzamiento. En altas concentraciones de la droga, el ARN celular y la síntesis de proteínas también se suprimen.
Oxaloplatino [Spanish]
Absorcion
No hay información disponible
Oxaloplatino [Spanish]
Toxicidad
No hay información disponible
Oxaloplatino [Spanish]
Informacion de Pacientes
Patients and patientsí caregivers should be informed of the expected side effects of ELOXATIN, particularly
its neurologic effects, both the acute, reversible effects, and the persistent neurosensory toxicity. Patients should
be informed that the acute neurosensory toxicity may be precipitated or exacerbated by exposure to cold or cold
objects. Patients should be instructed to avoid cold drinks, use of ice, and should cover exposed skin prior to
exposure to cold temperature or cold objects.
Patients must be adequately informed of the risk of low blood cell counts and instructed to contact their
physician immediately should fever, particularly if associated with persistent diarrhea, or evidence of infection
develop.
Patients should be instructed to contact their physician if persistent vomiting, diarrhea, signs of dehydration,
cough or breathing difficulties occur, or signs of allergic reaction appear.
Oxaloplatino [Spanish]
Organismos afectados
Humanos y otros mamíferos